Taking antidepressants is a major step for a lot of people who suffer from depression. Thereâs a lot of stigma against people with depression, and even more so against those who seek medicinal intervention in the form of medication. Because of the stigma, those who seek medication to help their depression are often uninformed about what antidepressants actually do.
Sometimes, they find that they arenât working the way that they thought they should. When the medication doesnât work, many people with depression are left wondering what their next step is. If youâve tried taking antidepressants to help with your symptoms of depression and found that they arenât working, hereâs what you need to know.
Here Are 7 Things You Should Know If Antidepressants don’t work for you
âIn an ideal world I guess we wouldnât get sick at all, but we have to settle for the fact that we do. Therefore, the next best scenario is we get sick, we get diagnosed, we get medicated, we get well.â – Jerry Kennard
1. Antidepressants do not always work
Dr. Jennifer Payne states, âWe have a vague understanding of how antidepressants work, but that doesn’t mean we totally understand the pharmacology. I don’t think anyone can offer a complete biological explanation for why antidepressants stop working. But I will say this: There are [factors] that can influence someone to relapse.â
According to research, at least one-third of people who seek medication donât find relief from their depression symptoms. This may be hard to hear, but sometimes medication just doesnât work when it comes to finding relief from depression. But once you know that, youâll be better equipped to find relief in other ways. Luckily, medication isnât the end all be all of the treatments for depression.
2. Science is still learning, whether you like it or not
Just because the medication isnât working for you now doesnât mean that itâll never work for you. Science is still learning and coming up with new theories every day. They continue to research antidepressants and why current medications donât seem to be working for those who take it. Thereâs new research every day focused on the best ways to find therapeutic relief to those suffering from depression.
3. It may not be depression, rather something different altogether
Psychology and mental health are fields that are highly subjective in many ways. This means that even though you may be experiencing all the symptoms of depression, that doesnât mean thatâs what you have. Other disorders can, and often do, show up as symptoms of depression – such as bipolar disorder and personality disorders. Depression can often be a symptom of something else, which may be why people donât respond to antidepressants.
4. Brains can adapt and learn to tolerate
According to this study, âAntidepressant tachyphylaxis describes a condition in which a depressed patient loses a previously effective antidepressant treatment response despite staying on the same drug and dosage for maintenance treatment.â
But what does this mean in laymanâs terms?
What most antidepressants do is increase your serotonin levels, which help combat most of the symptoms of depression and help you find relief. Sometimes, our brains adapt to the medication in ways that make it less effective. If youâve been on medication that seemed to help for a while but is no longer doing the trick, it might be that your brain has adapted to the medication. Some things might help this, such as an increased dose of the medication or a switch to a different type of antidepressant.
5. Therapy helps to reduce depression if antidepressants donât help
Many people forgo therapy because they feel like it doesnât help, but psychotherapy is a tried and true method that can help depressive symptoms. The thing about therapy, however, is that it takes time, effort, and dedication on the part of both the patient and the therapist. It can take years to achieve the full benefits of psychotherapy, but there are no possible side effects from therapy the way there are with medication. Before pursuing medical intervention, itâs important to seek out therapy as the first line of combating depression.
6. Make sure you get enough sleep
According to Dr. Lawrence J. Epstein, âPeople who have problems with sleep are at increased risk for developing emotional disorders, depression, and anxiety.â Therefore, when you first start your antidepressants, you want to make sure that youâre getting the recommended amount of sleep. Lack of sleep can cause instability in mood, and it can also affect how well your antidepressants are working. If you find that your antidepressants arenât working as they should, make sure youâre getting enough sleep. Studies find that patients who are getting the right amount of sleep have increased responses to antidepressant therapy.
7. Know your options
Antidepressants come in such a wide range of different options that a lot of people donât know what could work best for them. They may try one type of antidepressant and find that it doesnât work, so they give up entirely. If you find that youâre not responding well to one type of antidepressant, make sure to ask your doctor what other options there are. Antidepressants come in two main types, and you may respond better to one or the other. You also may need to add non-antidepressants that can help those medications work better, like a thyroid hormone or fish oil.
According to the chief of clinical psychiatry at Massachusetts General Hospital in Boston, Jonathan E. Alpert, MD, PhD, âThe rate of what used to be called Prozac poop-out — the rate of relapse on an antidepressant — is about 30% over a one-year period.â
Depression is a serious mental illness that affects so many people. The stigma surrounding medication can make knowing how to deal with your depressive symptoms that much harder – and when the medication doesnât work, you may be left wondering where to turn.
Thankfully, thereâs so much about medication for depression that your doctor can help you understand. As long as youâre honest and thorough about how your depression is responding to the medication, your doctor will be able to help you find the right treatment for you – and who knows, the right treatment may not be medication at all!
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